%0 Journal Article %T Systematic review and meta-analysis of cognitive impairment in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) %+ Centre de Recherche en Psychologie : Cognition, Psychisme et Organisations - UR UPJV 7273 (CRP-CPO) %A Aoun Sebaiti, Mehdi %A Hainselin, Mathieu %A Gounden, Yannick %A Sirbu, Carmen Adella %A Sekulic, Slobodan %A Lorusso, Lorenzo %A Nacul, Luis %A Authier, François Jérôme %< avec comité de lecture %@ 2045-2322 %J Scientific Reports %I Nature Publishing Group %V 12 %N 1 %P 2157 %8 2022-02-09 %D 2022 %R 10.1038/s41598-021-04764-w %Z Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior %Z Humanities and Social Sciences/Psychology %Z Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health %Z Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences %Z Life Sciences [q-bio]/Human health and pathologyJournal articles %X Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is commonly associated with cognitive complaints. To bring out the neuropsychological symptomatology inherent to ME/CFS, we conducted a systematic review according to PRISMA and MOOSE guidelines of the literature through the analysis of 764 studies published between 1988 and 2019 by using PubMed Central website and Clarivate analytics platform. We performed a meta-analysis to delineate an idea of the neuropsychological profile inherent in ME/CFS. The clinical picture typically affects visuo-spatial immediate memory (g = − 0.55, p = 0.007), reading speed (g = − 0.82, p = 0.0001) and graphics gesture (g = − 0.59, p = 0.0001). Analysis also revealed difficulties in several processes inherent in episodic verbal memory (storage, retrieval, recognition) and visual memory (recovery) and a low efficiency in attentional abilities. Executive functions seemed to be little or not affected and instrumental functions appeared constantly preserved. With regard to the complexity and heterogeneity of the cognitive phenotype, it turns out that determining a sound clinical picture of ME/CFS cognitive profile must go through a neuropsychological examination allowing a complete evaluation integrating the notion of agreement between the choice and the number of tests and the complexity intrinsic to the pathology. %G English %2 https://hal.science/hal-03563198/document %2 https://hal.science/hal-03563198/file/Aoun%20Sebaiti%202022%20-%20Systematic%20review%20and%20meta-analysis%20of%20cognitive%20impairment%20in%20myalgic%20encephalomyelitis%20chronic%20fatigue%20syndrome%20MECFS.pdf %L hal-03563198 %U https://hal.science/hal-03563198 %~ SHS %~ UNIV-PICARDIE %~ U-PICARDIE %~ CRP-CPO