@article{bar:hal-03576418, TITLE = {{Individualized hemodynamic optimization guided by indirect measurement of the respiratory exchange ratio in major surgery: study protocol for a randomized controlled trial (the OPHIQUE study)}}, AUTHOR = {Bar, Stephane and Boivin, Pierre and El Amine, Younes and Descamps, Richard and Moussa, Mouhamed and Abou Arab, Osama and Fischer, Marc-Olivier and Dupont, Herve and Lorne, Emmanuel and Guinot, Pierre-Gregoire}, URL = {https://u-picardie.hal.science/hal-03576418}, JOURNAL = {{Trials}}, PUBLISHER = {{BioMed Central}}, VOLUME = {21}, NUMBER = {1}, YEAR = {2020}, DOI = {10.1186/s13063-020-04879-x}, HAL_ID = {hal-03576418}, HAL_VERSION = {v1}, }