%0 Journal Article %T Effect of Six-Minute Walk Test and Incremental Exercise on Inspiratory Capacity, Ventilatory Constraints, Breathlessness and Exercise Performance in Sedentary Male Smokers without Airway Obstruction %+ Adaptations Physiologiques à l'Exercice et Réadaptation à l'effort - UR UPJV 3300 (APERE) %+ Département de génie électrique (Université de Moncton) %A Melliti, Wassim %A Kammoun, Rim %A Masmoudi, Donies %A Ahmaidi, Said %A Masmoudi, Kaouthar %A Alassery, Fawaz %A Hamam, Habib %A Chlif, Mehdi %< avec comité de lecture %@ 1661-7827 %J International Journal of Environmental Research and Public Health %I MDPI %V 18 %N 23 %8 2021 %D 2021 %R 10.3390/ijerph182312665 %Z Life Sciences [q-bio]Journal articles %X We investigated physiological responses and exercise capacity in sedentary young smokers during sub-maximal and maximal test and its impact on dyspnea and exercise intolerance. Fifty sedentary male smokers and non-smokers (age: 24 +/- 1 years., weight: 71 +/- 9 kg, height: 177.3 +/- 4.8 cm, body mass index: 22.6 +/- 2.5 kg/m(2)) underwent two visits with pulmonary function tests, breathing pattern, and inspiratory capacity measurement at rest and during sub-maximal and maximal exercise. Smokers show reduced exercise capacity during six minutes walk test (6-MWT) with decreased walked distance (p < 0.001) and inspiratory capacity (p < 0.05). During cardiopulmonary exercise test (CPET), smokers had higher minute ventilation VE for a given submaximal intensity (p < 0.05) and lower minute ventilation at maximal exercise (p < 0.001). End expiratory lung volume was significantly lower in sedentary smokers at rest (p < 0.05), at ventilatory threshold during exercise (p < 0.05), but not during peak exercise. End inspiratory lung volume was significantly lower in smokers at rest (p < 0.05) and ventilatory threshold (p < 0.05). Cigarette smoking alters lung function during submaximal and maximal exercise. This alteration is manifested by the development of dynamic hyperinflation contributing to exercise capacity limitation. %G English %L hal-03594530 %U https://u-picardie.hal.science/hal-03594530 %~ UNIV-PICARDIE %~ U-PICARDIE %~ APERE