%0 Journal Article %T Prognostic significance of pulsatile tinnitus in cervical artery dissection %+ Heidelberg University Hospital [Heidelberg] %+ Bordeaux population health (BPH) %+ Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 (TCDV) %+ Università degli Studi di Perugia = University of Perugia (UNIPG) %+ University Hospitals Leuven [Leuven] %+ Physiopathologie et imagerie des troubles neurologiques (PhIND) %+ Service de Neurologie [CHU Caen] %+ Laboratoire de Neurosciences Fonctionnelles et Pathologies - UR UPJV 4559 (LNFP) %+ CHU Amiens-Picardie %A Kellert, L. %A Kloss, M. %A Pezzini, A. %A Debette, S. %A Leys, D. %A Caso, V. %A Thijs, V. %A Bersano, A. %A Touzé, E. %A Tatlisumak, T. %A Traenka, C. %A Lyrer, P. %A Engelter, S. %A Metso, T. %A Grond-Ginsbach, C. %A Canaple, Sandrine %A Godefroy, Olivier %< avec comité de lecture %@ 1351-5101 %J European Journal of Neurology %I Wiley %V 23 %N 7 %P 1183-1187 %8 2016-07 %D 2016 %R 10.1111/ene.13031 %K acute ischaemic stroke %K cervical artery dissection %K outcome %K pulsatile tinnitus %Z Life Sciences [q-bio]/Human health and pathologyJournal articles %X Background and purpose: Our aim was to investigate whether pulsatile tinnitus (PT) in cervical artery dissection (CeAD) has prognostic significance.Methods: All CeAD patients from the CADISP (Cervical Artery Dissection and Ischemic Stroke Patients) study with documentation of PT were analysed. The presence of PT was systematically assessed using a standardized questionnaire. Stroke severity at admission was defined according to the National Institutes of Health Stroke Scale (NIHSS). Excellent outcome after 3 months was defined as a modified Rankin Scale of 0-1.Results: Sixty-three of 778 patients (8.1%) reported PT. PT+ patients presented less often with ischaemic stroke (41.3% vs. 63.9%, P < 0.001), more often with dissection in the internal carotid artery (85.7% vs. 64.2%, P = 0.001), less often with vessel occlusion (19.0% vs. 34.1%, P = 0.017) and more often with excellent outcome at 3 months (92.1% vs. 75.4%, P = 0.002). Logistic regression analysis identified PT as an independent predictor of excellent outcome after 3 months [odds ratio (OR) 3.96, 95% confidence interval (CI) 1.22-12.87] adjusted to significant outcome predictors NIHSS on admission (OR 0.82, 95% CI 0.79-0.86), Horner syndrome (OR 1.95, 95% CI 1.16-3.29) and vessel occlusion (OR 0.62, 95% CI 0.40-0.94) and to non-significant predictors age, sex, pain and location of CeAD.Conclusion: The presence of PT in CeAD is associated with a benign clinical course and predicts a favourable outcome. %G English %Z Cervical Artery Dissection and Ischemic Stroke Patients (CADISP) study group %L hal-04066665 %U https://u-picardie.hal.science/hal-04066665 %~ UNIV-PICARDIE %~ COMUE-NORMANDIE %~ UNICAEN %~ U1219 %~ U-PICARDIE %~ LNFP