<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-04946620</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-15T00:15:56+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Semi-synthetic cannabinoids: Literature review and update</title>
            <title xml:lang="fr">Les cannabinoïdes semi-synthétiques : revue de la littérature et mise à jour</title>
            <author role="aut">
              <persName>
                <forename type="first">Camille</forename>
                <surname>André</surname>
              </persName>
              <email type="md5">84bf39237da0eed01fde08b50fb3c094</email>
              <email type="domain">u-picardie.fr</email>
              <idno type="idhal" notation="numeric">954439</idno>
              <idno type="halauthorid" notation="string">815774-954439</idno>
              <idno type="IDREF">https://www.idref.fr/267614829</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/AAB-4840-2022</idno>
              <idno type="ORCID">https://orcid.org/0009-0004-6346-6809</idno>
              <affiliation ref="#struct-300535"/>
              <affiliation ref="#struct-580112"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Antoine</forename>
                <surname>Baudriller</surname>
              </persName>
              <idno type="halauthorid">3053072-0</idno>
              <affiliation ref="#struct-109058"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marie</forename>
                <surname>Bellouard</surname>
              </persName>
              <idno type="halauthorid">2818589-0</idno>
              <affiliation ref="#struct-300090"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Coralie</forename>
                <surname>Boudin</surname>
              </persName>
              <idno type="halauthorid">3280109-0</idno>
              <affiliation ref="#struct-1042703"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marie</forename>
                <surname>Carles</surname>
              </persName>
              <idno type="halauthorid">1391249-0</idno>
              <affiliation ref="#struct-1217339"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Alexandr</forename>
                <surname>Gish</surname>
              </persName>
              <email type="md5">947254706d6eecc43046396c9763fc13</email>
              <email type="domain">chu-lille.fr</email>
              <idno type="idhal" notation="string">alexandrgish</idno>
              <idno type="idhal" notation="numeric">1586440</idno>
              <idno type="halauthorid" notation="string">2221567-1586440</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-3083-9304</idno>
              <affiliation ref="#struct-425779"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Angéline</forename>
                <surname>Kernalleguen</surname>
              </persName>
              <idno type="halauthorid">3413830-0</idno>
              <affiliation ref="#struct-480788"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Maxime</forename>
                <surname>Kolmayer</surname>
              </persName>
              <idno type="halauthorid">2693411-0</idno>
              <affiliation ref="#struct-248633"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Edouard</forename>
                <surname>Le Carpentier</surname>
              </persName>
              <idno type="halauthorid">3413831-0</idno>
              <affiliation ref="#struct-474972"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marie</forename>
                <surname>Lenski</surname>
              </persName>
              <idno type="halauthorid">2510504-0</idno>
              <affiliation ref="#struct-171461"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Mohamed-Ali</forename>
                <surname>Rahali</surname>
              </persName>
              <idno type="halauthorid">3413832-0</idno>
              <affiliation ref="#struct-182194"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean-Joseph</forename>
                <surname>Bendjilali-Sabiani</surname>
              </persName>
              <idno type="halauthorid">3155485-0</idno>
              <affiliation ref="#struct-93599"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Alice</forename>
                <surname>Ameline</surname>
              </persName>
              <email type="md5">ba9304f7b320acccb329481ae42973b8</email>
              <email type="domain">unistra.fr</email>
              <idno type="idhal" notation="numeric">796869</idno>
              <idno type="halauthorid" notation="string">1641556-796869</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-1117-0887</idno>
              <affiliation ref="#struct-73897"/>
              <affiliation ref="#struct-1003040"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Louise</forename>
                <surname>DESSAIVRE</surname>
              </persName>
              <email type="md5">685d55eef963fb90de2023edc9d11c27</email>
              <email type="domain">u-picardie.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2025-02-13 17:22:16</date>
              <date type="whenModified">2025-11-27 16:06:16</date>
              <date type="whenReleased">2025-02-13 17:22:16</date>
              <date type="whenProduced">2025-02</date>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="799781">
                <persName>
                  <forename>Louise</forename>
                  <surname>DESSAIVRE</surname>
                </persName>
                <email type="md5">685d55eef963fb90de2023edc9d11c27</email>
                <email type="domain">u-picardie.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-04946620</idno>
            <idno type="halUri">https://u-picardie.hal.science/hal-04946620</idno>
            <idno type="halBibtex">andre:hal-04946620</idno>
            <idno type="halRefHtml">&lt;i&gt;Toxicologie Analytique et Clinique&lt;/i&gt;, 2025, 37 (2), pp.204-222. &lt;a target="_blank" href="https://dx.doi.org/10.1016/j.toxac.2025.01.101"&gt;&amp;#x27E8;10.1016/j.toxac.2025.01.101&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Toxicologie Analytique et Clinique, 2025, 37 (2), pp.204-222. &amp;#x27E8;10.1016/j.toxac.2025.01.101&amp;#x27E9;</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="UNIV-RENNES1">Université de Rennes 1</idno>
            <idno type="stamp" n="UGA">HAL Grenoble Alpes</idno>
            <idno type="stamp" n="UNIV-PICARDIE">Université de Picardie Jules Verne</idno>
            <idno type="stamp" n="UNIV-ANGERS">Université d'Angers</idno>
            <idno type="stamp" n="APHP" corresp="INSERM">AP-HP</idno>
            <idno type="stamp" n="UNIV-STRASBG">Université de Strasbourg</idno>
            <idno type="stamp" n="IFR140">SFR Biosit - Biologie et Santé CNRS UMS 3480</idno>
            <idno type="stamp" n="IRSET">Institut de Recherche en Santé, Environnement et Travail</idno>
            <idno type="stamp" n="IRSET-TREC" corresp="IRSET">TRANSCRIPTION, ENVIRONMENT and CANCER (TREC)</idno>
            <idno type="stamp" n="IRSET-NEED" corresp="IRSET">NEUROENDOCRINE EFFECTS OF ENDOCRINE DISRUPTORS</idno>
            <idno type="stamp" n="IRSET-TNGC" corresp="IRSET">Recherches épidémiologiques sur l'environnement, la reproduction et le développement</idno>
            <idno type="stamp" n="NUMECAN">Nutrition, Métabolismes et Cancer</idno>
            <idno type="stamp" n="UR1-UFR-SVE">UFR SVE Sciences de la vie et de l'environnement</idno>
            <idno type="stamp" n="UR1-HAL">Publications labos UR1 dans HAL-Rennes 1</idno>
            <idno type="stamp" n="UR1-SDV">UR1 - publications SDV</idno>
            <idno type="stamp" n="IRSET-1" corresp="IRSET">FARDEL - Contaminants environnementaux et barrière pulmonaire (ECPB)</idno>
            <idno type="stamp" n="TEST-UR-CSS">TEST Université de Rennes CSS</idno>
            <idno type="stamp" n="SITE-ALSACE">Archive ouverte du site Alsace</idno>
            <idno type="stamp" n="UNIV-RENNES">Université de Rennes</idno>
            <idno type="stamp" n="UNIV-LILLE">Université de Lille</idno>
            <idno type="stamp" n="INRAE">Institut National de Recherche en Agriculture, Alimentation et Environnement</idno>
            <idno type="stamp" n="IRSET-11" corresp="IRSET">Irset NAUDET - équipe 11</idno>
            <idno type="stamp" n="UGA-EPE">Université Grenoble Alpes [2020-*]</idno>
            <idno type="stamp" n="UR1-BIO-SA">Pôle UnivRennes - Biologie-Santé</idno>
            <idno type="stamp" n="U-PICARDIE">Université de Picardie Jules Verne</idno>
            <idno type="stamp" n="GRAP" corresp="U-PICARDIE">Groupe de Recherche sur l'alcool et les pharmacodépendances - UMR INSERM_S 1247</idno>
            <idno type="stamp" n="UNIVOAK">UNIVOAK</idno>
            <idno type="stamp" n="LPTNC">Laboratoire de pharmacologie et toxicologie neurocardiovasculaire</idno>
            <idno type="stamp" n="TEST-UGA">TEST-UGA</idno>
            <idno type="stamp" n="IMPECS">Impact de l'environnement chimique sur la santé humaine</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Semi-synthetic cannabinoids: Literature review and update</title>
                <title xml:lang="fr">Les cannabinoïdes semi-synthétiques : revue de la littérature et mise à jour</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Camille</forename>
                    <surname>André</surname>
                  </persName>
                  <email type="md5">84bf39237da0eed01fde08b50fb3c094</email>
                  <email type="domain">u-picardie.fr</email>
                  <idno type="idhal" notation="numeric">954439</idno>
                  <idno type="halauthorid" notation="string">815774-954439</idno>
                  <idno type="IDREF">https://www.idref.fr/267614829</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/AAB-4840-2022</idno>
                  <idno type="ORCID">https://orcid.org/0009-0004-6346-6809</idno>
                  <affiliation ref="#struct-300535"/>
                  <affiliation ref="#struct-580112"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Antoine</forename>
                    <surname>Baudriller</surname>
                  </persName>
                  <idno type="halauthorid">3053072-0</idno>
                  <affiliation ref="#struct-109058"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marie</forename>
                    <surname>Bellouard</surname>
                  </persName>
                  <idno type="halauthorid">2818589-0</idno>
                  <affiliation ref="#struct-300090"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Coralie</forename>
                    <surname>Boudin</surname>
                  </persName>
                  <idno type="halauthorid">3280109-0</idno>
                  <affiliation ref="#struct-1042703"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marie</forename>
                    <surname>Carles</surname>
                  </persName>
                  <idno type="halauthorid">1391249-0</idno>
                  <affiliation ref="#struct-1217339"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Alexandr</forename>
                    <surname>Gish</surname>
                  </persName>
                  <email type="md5">947254706d6eecc43046396c9763fc13</email>
                  <email type="domain">chu-lille.fr</email>
                  <idno type="idhal" notation="string">alexandrgish</idno>
                  <idno type="idhal" notation="numeric">1586440</idno>
                  <idno type="halauthorid" notation="string">2221567-1586440</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-3083-9304</idno>
                  <affiliation ref="#struct-425779"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Angéline</forename>
                    <surname>Kernalleguen</surname>
                  </persName>
                  <idno type="halauthorid">3413830-0</idno>
                  <affiliation ref="#struct-480788"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Maxime</forename>
                    <surname>Kolmayer</surname>
                  </persName>
                  <idno type="halauthorid">2693411-0</idno>
                  <affiliation ref="#struct-248633"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Edouard</forename>
                    <surname>Le Carpentier</surname>
                  </persName>
                  <idno type="halauthorid">3413831-0</idno>
                  <affiliation ref="#struct-474972"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marie</forename>
                    <surname>Lenski</surname>
                  </persName>
                  <idno type="halauthorid">2510504-0</idno>
                  <affiliation ref="#struct-171461"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Mohamed-Ali</forename>
                    <surname>Rahali</surname>
                  </persName>
                  <idno type="halauthorid">3413832-0</idno>
                  <affiliation ref="#struct-182194"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean-Joseph</forename>
                    <surname>Bendjilali-Sabiani</surname>
                  </persName>
                  <idno type="halauthorid">3155485-0</idno>
                  <affiliation ref="#struct-93599"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Alice</forename>
                    <surname>Ameline</surname>
                  </persName>
                  <email type="md5">ba9304f7b320acccb329481ae42973b8</email>
                  <email type="domain">unistra.fr</email>
                  <idno type="idhal" notation="numeric">796869</idno>
                  <idno type="halauthorid" notation="string">1641556-796869</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-1117-0887</idno>
                  <affiliation ref="#struct-73897"/>
                  <affiliation ref="#struct-1003040"/>
                </author>
              </analytic>
              <monogr>
                <idno type="localRef">LS7</idno>
                <idno type="halJournalId" status="VALID">114491</idno>
                <idno type="issn">2352-0078</idno>
                <title level="j">Toxicologie Analytique et Clinique</title>
                <imprint>
                  <publisher>Elsevier</publisher>
                  <biblScope unit="volume">37</biblScope>
                  <biblScope unit="issue">2</biblScope>
                  <biblScope unit="pp">204-222</biblScope>
                  <date type="datePub">2025-02</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1016/j.toxac.2025.01.101</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="fr">French</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Semi-synthetic cannabinoids</term>
                <term xml:lang="en">Analytical aspects</term>
                <term xml:lang="en">Pharmacological properties</term>
                <term xml:lang="en">Literature review</term>
                <term xml:lang="fr">Cannabinoïdes semi-synthétiques</term>
                <term xml:lang="fr">Revue de la littérature</term>
                <term xml:lang="fr">Propriétés pharmacologiques</term>
                <term xml:lang="fr">Aspects analytiques</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv.tox">Life Sciences [q-bio]/Toxicology</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Semi-synthetic cannabinoids are analogues of natural cannabinoids whose chemical structure has been modified to improve their therapeutic profile or broaden their scope of application. These modifications increase the selectivity, potency or stability of the substances, while minimizing undesirable side effects. However, these substances are not without risks, especially when diverted for recreational use. The main semi-synthetic cannabinoids are Δ8-THC, HHC, 9R-11-Hydroxyhexahydrocannabinol or H2-CBD and H4-CBD. This review, which includes all the important information on semi-synthetic cannabinoids, allows an update of knowledge, concerning regulations, pharmacological properties, clinical and medico-legal data, as well as analytical aspects.</p>
            </abstract>
            <abstract xml:lang="fr">
              <p>Les cannabinoïdes semi-synthétiques sont des analogues des cannabinoïdes naturels dont la structure chimique a été modifiée pour améliorer leur profil thérapeutique ou élargir leur champ d’application. Ces modifications permettent d’augmenter la sélectivité, la puissance ou encore la stabilité des substances, tout en minimisant les effets secondaires indésirables. Cependant, ces substances ne sont pas sans risques, surtout lorsqu’elles sont détournées pour un usage récréatif. Les principaux cannabinoïdes semi-synthétiques sont le Δ8-THC, le HHC, le 9R-11-Hydroxyhexahydrocannabinol ou encore le H2-CBD et le H4-CBD. Cette revue, reprenant l’ensemble des informations importantes sur les cannabinoïdes semi-synthétiques, permet une actualisation des connaissances, concernant la réglementation, les propriétés pharmacologiques, les données cliniques et médico-légales, ainsi que les aspects analytiques.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="institution" xml:id="struct-300535" status="VALID">
          <orgName>CHU Amiens-Picardie</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-580112" status="VALID">
          <idno type="IdRef">195706684</idno>
          <idno type="RNSR">200720140R</idno>
          <idno type="ROR">https://ror.org/01c62av11</idno>
          <orgName>Groupe de Recherche sur l'alcool et les pharmacodépendances - UMR INSERM_S 1247 UPJV</orgName>
          <orgName type="acronym">GRAP</orgName>
          <date type="start">2007-01-01</date>
          <desc>
            <address>
              <addrLine>Université de Picardie Jules Verne - CURS - CHU Sud - avenue Laënnec - 80054 AMIENS CEDEX 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://grap.u-picardie.fr</ref>
          </desc>
          <listRelation>
            <relation name="ERI24" active="#struct-300258" type="direct"/>
            <relation name="U1247" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-109058" status="VALID">
          <orgName>Département de Pharmacologie-Toxicologie [CHU Angers]</orgName>
          <desc>
            <address>
              <addrLine>Département de Pharmacolgie-Toxicologie, CHU d'Angers, 4 rue Larrey, 49933 Angers Cedex 09</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-angers.fr/offre-de-soins/pharmacologie-toxicologie-78024.kjsp</ref>
          </desc>
          <listRelation>
            <relation active="#struct-151939" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300090" status="VALID">
          <idno type="ROR">https://ror.org/03pef0w96</idno>
          <orgName>Hôpital Raymond Poincaré [AP-HP]</orgName>
          <desc>
            <address>
              <addrLine>104 Boulevard Raymond Poincaré, 92380 Garches</addrLine>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-1042703" status="VALID">
          <idno type="IdRef">240648315</idno>
          <idno type="ROR">https://ror.org/02rx3b187</idno>
          <orgName>Université Grenoble Alpes</orgName>
          <orgName type="acronym">UGA</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Adresse CS 40700 - 38058 Grenoble cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-grenoble-alpes.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1217339" status="INCOMING">
          <orgName>PRISM Biogénopôle La Timone University Hospital of Marseille, APHM, Marseille, France</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-425779" status="VALID">
          <idno type="IdRef">034424636</idno>
          <idno type="ISNI">0000000404718845</idno>
          <idno type="ROR">https://ror.org/02ppyfa04</idno>
          <idno type="Wikidata">Q2945741</idno>
          <orgName>Centre Hospitalier Régional Universitaire [CHU Lille]</orgName>
          <orgName type="acronym">CHRU Lille</orgName>
          <desc>
            <address>
              <addrLine>CHU/CHRU Lille - 2, avenue Oscar Lambret - 59037 Lille Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chru-lille.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-480788" status="VALID">
          <idno type="IdRef">28086812X</idno>
          <idno type="RNSR">201722267J</idno>
          <idno type="ROR">https://ror.org/03zb6nw87</idno>
          <orgName>Nutrition, Métabolismes et Cancer</orgName>
          <orgName type="acronym">NuMeCan</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Campus Villejean (Bât 8) - CHU Rennes (Bât 15) - Université de Rennes 1, 2 Avenue du Professeur Léon Bernard, 35043 Rennes, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://numecan.univ-rennes.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-105160" type="direct"/>
            <relation name="U1317 / UMR1317" active="#struct-303623" type="direct"/>
            <relation name="UMR 1341" active="#struct-577435" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-248633" status="VALID">
          <orgName>Centre Hospitalier Emile Durkheim [Epinal]</orgName>
          <orgName type="acronym">CH Epinal / CHED</orgName>
          <desc>
            <address>
              <addrLine>3 avenue R. Schuman, 88021 Epinal cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ch-emile-durkheim.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-474972" status="VALID">
          <idno type="IdRef">034926445</idno>
          <idno type="ROR">https://ror.org/05c1qsg97</idno>
          <idno type="Wikidata">Q2945767</idno>
          <orgName>Centre Hospitalier Universitaire de Nantes = Nantes University Hospital</orgName>
          <orgName type="acronym">CHU Nantes</orgName>
          <desc>
            <address>
              <addrLine>1 Place Alexis-Ricordeau, 44000 Nantes</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-nantes.fr</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-171461" status="VALID">
          <idno type="IdRef">201012707</idno>
          <idno type="ISNI">0000000512425804</idno>
          <idno type="RNSR">201019074U</idno>
          <idno type="ROR">https://ror.org/0455vgw31</idno>
          <idno type="Wikidata">Q116959446</idno>
          <orgName>Impact de l'environnement chimique sur la santé humaine - ULR 4483</orgName>
          <orgName type="acronym">IMPECS</orgName>
          <date type="start">2002-01-01</date>
          <desc>
            <address>
              <addrLine>Pôle Recherche de la Faculté de Médecine - 3ème étage - Aile EST -1, place de Verdun - 59045 Lille Cédex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://recherche.univ-lille2.fr/fr/la-recherche/annuequipes/sciencesviesante/ea/ea-4483.html</ref>
          </desc>
          <listRelation>
            <relation name="EA4483" active="#struct-374570" type="direct"/>
            <relation active="#struct-425779" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-182194" status="VALID">
          <idno type="IdRef">177984775</idno>
          <idno type="RNSR">201722263E</idno>
          <idno type="ROR">https://ror.org/01p178v10</idno>
          <idno type="Wikidata">Q30261433</idno>
          <orgName>Institut de recherche en santé, environnement et travail</orgName>
          <orgName type="acronym">Irset</orgName>
          <date type="start">2009-01-01</date>
          <desc>
            <address>
              <addrLine>263 avenue Général Leclerc 35042 Rennes Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.irset.org</ref>
          </desc>
          <listRelation>
            <relation active="#struct-74911" type="direct"/>
            <relation active="#struct-105160" type="direct"/>
            <relation active="#struct-301986" type="direct"/>
            <relation name="U1085" active="#struct-303623" type="direct"/>
            <relation active="#struct-453207" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-93599" status="VALID">
          <idno type="ROR">https://ror.org/00mthsf17</idno>
          <orgName>CHU Montpellier = Montpellier University Hospital</orgName>
          <desc>
            <address>
              <addrLine>371, avenue du Doyen Gaston Giraud 34295 MONTPELLIER cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-montpellier.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-258773" type="direct"/>
          </listRelation>
        </org>
        <org type="regrouplaboratory" xml:id="struct-73897" status="VALID">
          <orgName>Institut de Médecine Légale [Strasbourg]</orgName>
          <desc>
            <address>
              <addrLine>11, rue Humann 67085 Strasbourg Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www-ulpmed.u-strasbg.fr/iml/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-199013" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1003040" status="VALID">
          <idno type="IdRef">176973567</idno>
          <idno type="RNSR">201320499E</idno>
          <idno type="ROR">https://ror.org/028c6kd10</idno>
          <idno type="Wikidata">Q51783098</idno>
          <orgName>Laboratoire de pharmacologie et toxicologie neurocardiovasculaire</orgName>
          <orgName type="acronym">LPTNC</orgName>
          <desc>
            <address>
              <addrLine>Faculté de médecine11 rue Humann67000 Strasbourg</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation name="UR7296 / EA7296" active="#struct-199013" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300258" status="VALID">
          <idno type="IdRef">026403714</idno>
          <idno type="ISNI">0000 0001 0789 1385</idno>
          <idno type="ROR">https://ror.org/01gyxrk03</idno>
          <orgName>Université de Picardie Jules Verne</orgName>
          <orgName type="acronym">UPJV</orgName>
          <desc>
            <address>
              <addrLine>Chemin du Thil - 80000 Amiens</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.u-picardie.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-151939" status="VALID">
          <idno type="ISNI">0000 0004 0472 0283</idno>
          <idno type="ROR">https://ror.org/0250ngj72</idno>
          <orgName>Centre Hospitalier Universitaire d'Angers</orgName>
          <orgName type="acronym">CHU Angers</orgName>
          <desc>
            <address>
              <addrLine>4 rue Larrey - 49933 Angers cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-angers.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-105160" status="VALID">
          <idno type="IdRef">26693823X</idno>
          <idno type="ROR">https://ror.org/015m7wh34</idno>
          <orgName>Université de Rennes</orgName>
          <orgName type="acronym">UR</orgName>
          <desc>
            <address>
              <addrLine>Campus de Beaulieu, 263 avenue Général Leclerc, CS 74205, 35042 RENNES CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-rennes.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-577435" status="VALID">
          <idno type="ROR">https://ror.org/003vg9w96</idno>
          <orgName>Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement</orgName>
          <orgName type="acronym">INRAE</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-374570" status="VALID">
          <idno type="IdRef">223446556</idno>
          <idno type="ISNI">0000 0001 2242 6780</idno>
          <idno type="ROR">https://ror.org/02kzqn938</idno>
          <idno type="Wikidata">Q3551621</idno>
          <orgName>Université de Lille</orgName>
          <desc>
            <address>
              <addrLine>EPE Université de Lille. -- 42 rue Paul Duez, 59000 Lille</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-lille.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-74911" status="VALID">
          <idno type="IdRef">026402920</idno>
          <idno type="ISNI">0000000122483363</idno>
          <idno type="ROR">https://ror.org/04yrqp957</idno>
          <orgName>Université d'Angers</orgName>
          <orgName type="acronym">UA</orgName>
          <date type="start">1971-10-25</date>
          <desc>
            <address>
              <addrLine>Université d'Angers - 40 Rue de Rennes, BP 73532 - 49035 Angers CEDEX 01</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-angers.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301986" status="VALID">
          <idno type="IdRef">161356915</idno>
          <idno type="ISNI">0000 0001 1943 5037</idno>
          <idno type="ROR">https://ror.org/01sc83v92</idno>
          <orgName>École des Hautes Études en Santé Publique</orgName>
          <orgName type="acronym">EHESP</orgName>
          <date type="start">2008-01-01</date>
          <desc>
            <address>
              <addrLine>15, avenue du Pr. Léon Bernard - 35043 Rennes Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ehesp.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-453207" status="VALID">
          <idno type="IdRef">200295462</idno>
          <idno type="RNSR">201220717W</idno>
          <idno type="ROR">https://ror.org/05cx7ek10</idno>
          <orgName>Structure Fédérative de Recherche en Biologie et Santé de Rennes</orgName>
          <orgName type="acronym">Biosit : Biologie - Santé - Innovation Technologique</orgName>
          <date type="start">2012-01-01</date>
          <desc>
            <address>
              <addrLine>Université de Rennes - Campus Santé Villejean -  2, avenue Professeur Léon Bernard 35043 Rennes cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://biosit.univ-rennes.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-258773" status="VALID">
          <idno type="ISNI">000000009961060X</idno>
          <idno type="ROR">https://ror.org/04m6sq715</idno>
          <orgName>Centre Hospitalier Régional Universitaire [Montpellier]</orgName>
          <orgName type="acronym">CHRU Montpellier</orgName>
          <desc>
            <address>
              <addrLine>191 avenue du doyen Gaston Giraud 34295 Montpellier</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-montpellier.fr/fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-199013" status="VALID">
          <idno type="IdRef">131056549</idno>
          <idno type="ROR">https://ror.org/00pg6eq24</idno>
          <orgName>Université de Strasbourg</orgName>
          <orgName type="acronym">UNISTRA</orgName>
          <desc>
            <address>
              <addrLine>4 rue Blaise Pascal - CS 90032 - 67081 Strasbourg cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.unistra.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>