Guidelines for the assessment and management of residual sleepiness in obstructive apnea-hypopnea syndrome. Endorsed by the French Sleep Research and Medicine Society (SFRMS) and the French Speaking Society of Respiratory Diseases (SPLF) - Université de Picardie Jules Verne Accéder directement au contenu
Article Dans Une Revue Respiratory Medicine and Research Année : 2024

Guidelines for the assessment and management of residual sleepiness in obstructive apnea-hypopnea syndrome. Endorsed by the French Sleep Research and Medicine Society (SFRMS) and the French Speaking Society of Respiratory Diseases (SPLF)

1 Hôpital Gui de Chauliac [CHU Montpellier]
2 INM - Institut des Neurosciences de Montpellier
3 HP2 - Hypoxie et PhysioPathologie
4 AGIR - Agents infectieux, résistance et chimiothérapie - UR UPJV 4294
5 CHU Amiens-Picardie
6 Inserm U955 - Molecular virology and immunology – Physiopathology and therapeutic of chronic viral hepatitis (Team 18)
7 UPE - Université Paris-Est
8 BAR - Biomécanique & Appareil Respiratoire
9 Hôpital Henri Mondor
10 CHI Créteil
11 PARCC (UMR_S 970/ U970) - Paris-Centre de Recherche Cardiovasculaire
12 UA - Université d'Angers
13 CHU Angers - Centre Hospitalier Universitaire d'Angers
14 AP-HP - Hôpital Bichat - Claude Bernard [Paris]
15 SANPSY - Sommeil, Addiction et Neuropsychiatrie [Bordeaux]
16 CHU de Bordeaux - Service Universitaire de Médecine du Sommeil
17 HPPIT - Hypertension pulmonaire : physiopathologie et innovation thérapeutique
18 Service de Pneumologie [AP-HP, Hôpital Bicêtre]
19 LilNCog - Lille Neurosciences & Cognition - U 1172
20 UMRS 1158 - Neurophysiologie Respiratoire Expérimentale et Clinique
21 CHU Pitié-Salpêtrière [AP-HP]
22 CHU de Bordeaux Pellegrin [Bordeaux]
23 UCL - Université Catholique de Louvain = Catholic University of Louvain
24 MITOVASC - MitoVasc - Physiopathologie Cardiovasculaire et Mitochondriale
25 CHRU Montpellier - Centre Hospitalier Régional Universitaire [Montpellier]
26 PhyMedExp - Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046]
27 ICM - Institut du Cerveau = Paris Brain Institute

Résumé

Excessive daytime sleepiness (EDS) is frequent among patients with obstructive sleep apnea hypopnea syndrome (OSAHS) and can persist despite the optimal correction of respiratory events (apnea, hypopnea and respiratory efforts), using continuous positive airway pressure (CPAP) or mandibular advancement device. Symptoms like apathy and fatigue may be mistaken for EDS. In addition, EDS has multi-factorial origin, which makes its evaluation complex. The marketing authorization [Autorisation de Mise sur le Marché (AMM)] for two wake-promoting agents (solriamfetol and pitolisant) raises several practical issues for clinicians. This consensus paper presents recommendations of good clinical practice to identify and evaluate EDS in this context, and to manage and follow-up the patients. It was conducted under the mandate of the French Societies for sleep medicine and for pneumology [Société Française de Recherche et de Médecine du Sommeil (SFRMS) and Société de Pneumologie de Langue Française (SPLF)]. A management algorithm is suggested, as well as a list of conditions during which the patient should be referred to a sleep center or a sleep specialist. The benefit/risk balance of a wake-promoting drug in residual EDS in OSAHS patients must be regularly reevaluated, especially in elderly patients with increased cardiovascular and psychiatric disorders risks. This consensus is based on the scientific knowledge at the time of the publication and may be revised according to their evolution.
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Dates et versions

hal-04543619 , version 1 (12-04-2024)

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Citer

Lucie Barateau, Sébastien Baillieul, Claire Andrejak, Émilie Bequignon, Pierre Boutouyrie, et al.. Guidelines for the assessment and management of residual sleepiness in obstructive apnea-hypopnea syndrome. Endorsed by the French Sleep Research and Medicine Society (SFRMS) and the French Speaking Society of Respiratory Diseases (SPLF). Respiratory Medicine and Research, 2024, pp.101105. ⟨10.1016/j.resmer.2024.101105⟩. ⟨hal-04543619⟩
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