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Article Dans Une Revue HPB Année : 2024

European Validation of the Classification for the Anticipated Difficulty of Liver Transplantation

Lazare Sommier
Josefina Lopez-Dominguez
  • Fonction : Auteur
Pauline Georges
Théo Poppen
  • Fonction : Auteur
Perrine Lioret
  • Fonction : Auteur
Francis Navarro
  • Fonction : Auteur
Bruno Heyd
Olivier Soubrane
  • Fonction : Auteur
Daniel Azoulay
Olivier Scatton
  • Fonction : Auteur

Résumé

BACKGROUND Appropriate risk stratification for the difficulty of liver transplantation (LT) is essential to guide the selection and acceptance of grafts and avoid morbidity and mortality. METHODS Based on 987 LTs collected from 5 centers, perioperative outcomes were analyzed across the 3 difficulty levels. Each LT was retrospectively scored from 0 to 10. Scores of 0-2, 3-5 and 6-10 were then translated into respective difficulty levels: low, moderate and high. Complications were reported according to the comprehensive complication index (CCI). RESULTS The difficulty level of LT in 524 (53%), 323 (32%), and 140 (14%) patients was classified as low, moderate and high, respectively. The values of major intraoperative outcomes, such as cold ischemia time (p=0.04) and operative time (p<0.0001) increased gradually with statistically significant values among difficulty levels. There was a corresponding increase in CCI (p=0.04), severe complication rates (p=0.05) and length of ICU (p=0.01) and hospital (p=0.004) stays across the different difficulty levels. CONCLUSIONS The LT difficulty classification has been validated.
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Dates et versions

hal-04578225 , version 1 (16-05-2024)

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Lazare Sommier, Chetana Lim, Florence Jeune, Claire Goumard, Célia Turco, et al.. European Validation of the Classification for the Anticipated Difficulty of Liver Transplantation. HPB, 2024, ⟨10.1016/j.hpb.2024.05.004⟩. ⟨hal-04578225⟩
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