Treatment of Bone and Joint Tuberculosis in France: A Multicentre Retrospective Study - Université de Picardie Jules Verne Accéder directement au contenu
Article Dans Une Revue Journal of Clinical Medicine Année : 2020

Treatment of Bone and Joint Tuberculosis in France: A Multicentre Retrospective Study

Résumé

Background: Nine percent of all cases of tuberculosis are bone and joint tuberculosis (BJTB). BJTB occurs in two main forms: spinal (STB) and extraspinal (ESTB). The aim of this study was to compare STB with ESTB in terms of diagnosis, treatment and outcomes. Methods: We collected demographic, clinical, microbiological, treatment duration and outcome data for patients with BJTB in a retrospective multicentre study over a 17-year period. Results: Of the 116 patients included in the study, 69 (59.5%) had STB and 47 (40.5%) had ESTB. The median age was higher in the ESTB group. There were significantly more foreign-born patients in the STB group. The median time for diagnosis was longer for ESTB (6 months) than STB (4 months) (p= 0.017). Magnetic resonance imaging was highly reliable for the diagnosis. Direct examination and histology allowed the diagnosis to be made in more than 80% of cases. The median treatment duration of 12 months, regardless of the type of BJTB, was longer than recommended. A favourable outcome was achieved in 91.9% of cases. Conclusion: The management of BJTB remains challenging. An earlier diagnosis should be more effective, reducing the total duration of treatment and leading to better tolerance.
Fichier principal
Vignette du fichier
jcm-09-02529-v2.pdf (755.03 Ko) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-03591322 , version 1 (18-12-2023)

Licence

Paternité

Identifiants

Citer

Aurelie Guillouzouic, Claire Andrejak, Olivia Peuchant, Genevieve Hery-Arnaud, Farida Hamdad, et al.. Treatment of Bone and Joint Tuberculosis in France: A Multicentre Retrospective Study. Journal of Clinical Medicine, 2020, 9 (8), pp.2529. ⟨10.3390/jcm9082529⟩. ⟨hal-03591322⟩
34 Consultations
4 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More