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Article Dans Une Revue American Journal of Neuroradiology Année : 2020

COVID-19 Neurologic Complication with CNS Vasculitis-Like Pattern

R. Hanafi
  • Fonction : Auteur
P-A Roger
  • Fonction : Auteur
B. Perin
  • Fonction : Auteur
G. Kuchcinski
  • Fonction : Auteur
N. Deleval
  • Fonction : Auteur
F. Dallery
  • Fonction : Auteur
D. Michel
  • Fonction : Auteur
L. Hacein-Bey
  • Fonction : Auteur
J-P Pruvo
  • Fonction : Auteur
O. Outteryck
  • Fonction : Auteur


Coronavirus disease 2019 (COVID-19) is a viral infection caused by the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), which spreads rapidly from person to person and manifests in most symptomatic patients as a respiratory illness, similar to prior SARS viruses. Neurologic manifestations of COVID-19 are uncommon; those so far reported include encephalopathy, stroke from large-vessel occlusion, and polyneuropathy. We report a unique neurologic complication of COVID-19 in a patient who had extensive cerebral small-vessel ischemic lesions resembling cerebral vasculitis in a characteristic combined imaging pattern of ischemia, hemorrhage, and punctuate postcontrast enhancement. Also, a characteristic lower extremity skin rash was present in our patient. Our observation lends support to the increasingly suspected mechanism of ``endotheliitis'' associated with this novel coronavirus.

Dates et versions

hal-03599519 , version 1 (07-03-2022)



R. Hanafi, P-A Roger, B. Perin, G. Kuchcinski, N. Deleval, et al.. COVID-19 Neurologic Complication with CNS Vasculitis-Like Pattern. American Journal of Neuroradiology, 2020, 41 (8), pp.1384-1387. ⟨10.3174/ajnr.A6651⟩. ⟨hal-03599519⟩


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