Cognitive disorders in patients with chronic kidney disease: Approaches to prevention and treatment
Marion Pépin
(1)
,
Aleksandra Klimkowicz-Mrowiec
,
Olivier Godefroy
(2, 3)
,
Pilar Delgado
(4)
,
Sol Carriazo
(5)
,
Ana Carina Ferreira
(6)
,
Aleksandra Golenia
,
Jolanta Malyszko
(7)
,
Tomasz Grodzicki
(8)
,
Konstantinos Giannakou
(9)
,
Giuseppe Paolisso
,
Michelangela Barbieri
(10)
,
Liliana Garneata
(11)
,
Carmen Antonia Mocanu
(12)
,
Sophie Liabeuf
(13, 14)
,
Goce Spasovski
(15)
,
Carmine Zoccali
(16, 17)
,
Annette Bruchfeld
,
Ana Farinha
(18)
,
Mustafa Arici
(19)
,
Giovambattista Capasso
,
Andrzej Wiecek
,
Ziad Massy
(1)
1
CESP -
Centre de recherche en épidémiologie et santé des populations
2 Service de neurologie [Amiens]
3 LNFP - Laboratoire de Neurosciences Fonctionnelles et Pathologies - UR UPJV 4559
4 Neurovascular Research Laboratory, Stroke Unit
5 FJD - Fundacion Jimenez Diaz [Madrid]
6 NOVA - Universidade Nova de Lisboa = NOVA University Lisbon
7 Medical University of Warsaw - Poland
8 UJ - Uniwersytet Jagielloński w Krakowie = Jagiellonian University
9 European University of Cyprus
10 Geriatric Medicine and Metabolic Diseases
11 Université de Médecine Carol Davila
12 UMPCD - University of Medicine and Pharmacy “Carol Davila” Bucharest
13 CHU Amiens-Picardie
14 MP3CV - Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517
15 Department of Nephrology [Skopje, Macedonia]
16 CNR-IFC Clinical Epidemiology and Pathophysiology of Renal Diseases and Hpertension Unit, Reggio Calabria
17 Ospedali Riuniti
18 Université de Lisbonne
19 Hacettepe University = Hacettepe Üniversitesi
2 Service de neurologie [Amiens]
3 LNFP - Laboratoire de Neurosciences Fonctionnelles et Pathologies - UR UPJV 4559
4 Neurovascular Research Laboratory, Stroke Unit
5 FJD - Fundacion Jimenez Diaz [Madrid]
6 NOVA - Universidade Nova de Lisboa = NOVA University Lisbon
7 Medical University of Warsaw - Poland
8 UJ - Uniwersytet Jagielloński w Krakowie = Jagiellonian University
9 European University of Cyprus
10 Geriatric Medicine and Metabolic Diseases
11 Université de Médecine Carol Davila
12 UMPCD - University of Medicine and Pharmacy “Carol Davila” Bucharest
13 CHU Amiens-Picardie
14 MP3CV - Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517
15 Department of Nephrology [Skopje, Macedonia]
16 CNR-IFC Clinical Epidemiology and Pathophysiology of Renal Diseases and Hpertension Unit, Reggio Calabria
17 Ospedali Riuniti
18 Université de Lisbonne
19 Hacettepe University = Hacettepe Üniversitesi
Marion Pépin
- Fonction : Auteur
- PersonId : 1170854
- ORCID : 0000-0002-3064-2480
Aleksandra Klimkowicz-Mrowiec
- Fonction : Auteur
- PersonId : 1264141
- ORCID : 0000-0001-7480-5723
Olivier Godefroy
- Fonction : Auteur
- PersonId : 901333
- ORCID : 0000-0001-6789-6620
- IdRef : 068994737
Aleksandra Golenia
- Fonction : Auteur
Giuseppe Paolisso
- Fonction : Auteur
Carmen Antonia Mocanu
- Fonction : Auteur
- PersonId : 1264142
- ORCID : 0000-0001-5147-6285
Sophie Liabeuf
- Fonction : Auteur
- PersonId : 750529
- IdHAL : sophieliabeuf
- ORCID : 0000-0001-5384-9006
- IdRef : 081054882
Annette Bruchfeld
- Fonction : Auteur
Giovambattista Capasso
- Fonction : Auteur
Andrzej Wiecek
- Fonction : Auteur
Ziad Massy
- Fonction : Auteur
- PersonId : 1003368
- ORCID : 0000-0001-5771-5996
Résumé
Cognitive impairment is common in patients with chronic kidney disease (CKD), and early intervention may prevent the progression of this condition. Here, we review interventions for the complications of CKD (anemia, secondary hyperparathyroidism, metabolic acidosis, harmful effects of dialysis, the accumulation of uremic toxins) and for prevention of vascular events, interventions that may potentially be protective against cognitive impairment. Furthermore, we discuss non-pharmacological and pharmacological methods to prevent cognitive impairment and/or minimize the latter's impact on CKD patients' daily lives.