Association Between Serum Phosphate Levels and Progression of Aortic Stenosis
Résumé
Aortic stenosis (AS) is a complex disease process involving fibrosis and calcification of the aortic valve leaflets. As there is no known effective medical therapy, the identification of modifiable risk factors for progression is a key objective. Epidemiological and pathophysiological evidence suggests a role of phosphate in the pathogenesis of cardiac valve calcification. We aimed to investigate the relationship between serum phosphate levels and the progression of AS.